Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation
Ishizaka, A., Koga, M., Mizutani, T., Parbie, P. K., Prawisuda, D., Yusa, N., Sedohara, A., Kikuchi, T., Ikeuchi, K., Adachi, E., Koibuchi, T., Furukawa, Y., Tojo, A., Imoto, S., Suzuki, Y., Tsutsumi, T., Kiyono, H., Matano, T., & Yotsuyanagi, H. (2021). Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation. Microbiology spectrum, 9(1), e0070821.
- The article investigated compositional changes in the gut microbiome and its role in chronic inflammation in patients infected with HIV. The results suggest that gut dysbiosis contributes to sustaining chronic inflammation in patients with HIV infection despite effective antiretroviral therapy and that correcting gut dysbiosis will be effective in improving long-term outcomes in patients.
