Does telehealth affect the adherence to ART among patients with HIV? A systematic review and meta-analysis
March 17, 2023Several studies have shown different effects of telehealth interventions on adherence to Antiretroviral therapy (ART) among people living with HIV. This study conducted a meta-analysis of Randomized Controlled Trials (RCTs) to estimate the pooled effect of telehealth interventions on the treatment adherence of HIV patients.
What is the HIV Care Continuum?
October 28, 2022This resource from HIV.gov describes the HIV care continuum, a public health model that outlines the steps or stages that people with HIV go through from diagnosis to achieving and maintaining viral suppression through care and treatment.
After ARVs
July 26, 2022Has the dawn of HIV therapeutic vaccines arrived at AIDS 2022?
Monocytes in HIV and SIV Infection and Aging: Implications for Inflamm-Aging and Accelerated Aging
February 17, 2022With ART and the extended lifespan of PLWH, HIV comorbidities also include aging—most likely due to accelerated aging—as well as cardiovascular, neurocognitive disorders, lung and kidney disease, and malignancies. The broad evidence suggests that HIV with ART is associated with accentuated aging and that the age-related comorbidities occur earlier, due in part to chronic immune activation, co-infections, and possibly the effects of ART alone.
HIV and Aging in the Era of ART and COVID-19
February 1, 2022Our understanding of HIV/AIDS has been reframed in the recent past because the use of novel antiretroviral therapy has enabled clinicians and patients to control the progression of the disease.
Multimorbidity in people with HIV using ART in the US: Projections to 2030
November 9, 2021Researchers forecast a “silver tsunami” in multimorbidity, polypharmacy, and healthcare costs in US residents with HIV.
Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation
August 11, 2021This article investigated compositional changes in the gut microbiome and its role in chronic inflammation in patients infected with HIV. The results suggest that gut dysbiosis contributes to sustaining chronic inflammation in patients with HIV infection despite effective antiretroviral therapy and that correcting gut dysbiosis will be effective in improving long-term outcomes in patients.
Aging with HIV in the ART Era
July 22, 2021This article from Seminars in Diagnostic Pathology examines the various comorbidities, such as chronic inflammation, associated with aging with HIV.
Forging New Frontiers in HIV and Aging
This editorial looks at the current state of ART, aging with HIV, and factors related to positive aging.
Long-Term Suppressive cART Is Not Sufficient to Restore Intestinal Permeability and Gut Microbiota Compositional Changes
February 26, 2021The study explores the long-term effects of cART on markers of gut damage, microbial translocation, and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes.
Oral and Gut Microbial Diversity and Immune Regulation in Patients with HIV on Antiretroviral Therapy
February 5, 2020The study aimed to determine the relationship between oral and gut microbiome diversity and chronic systemic inflammation in ART-treated PLWH with prevalent severe periodontitis, an inflammatory condition commonly associated with HIV infection.
A tale of two countries: all-cause mortality among people living with HIV and receiving combination antiretroviral therapy in the UK and Canada
January 17, 2017Canada and the United Kingdom have different provisions in health care services for those living with HIV. This study follows Canadians and UK citizens with HIV who started ART between 2000 and 2012. The researchers found that there was no significant difference in mortality rates between Canadians and UK citizens who got HIV through sexual transmission and were on ART.
